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Summary: Menstruation irregular could be caused by Lamisil, especially for people who are female, 30-39 old, have been taking the drug for < 1 month, also take Serzone, and have Anxiety.

We study 6,886 people who have side effects while taking Lamisil from FDA and social media. Among them, 6 have Menstruation irregular. Find out below who they are, when they have Menstruation irregular and more.

 

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1. Duodenal Infusion of Donor Feces for recurrent Clostridium difficile

http://www.nejm.org/doi/full/10.1056/NEJMoa1205037?query=featured_home

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月經週期會惡化的皮膚病有:
痘痘, 皰疹樣皮膚炎, 多行性紅斑, 扁平苔癬, 狼瘡, 乾癬, 黃體素皮膚炎, 動情素皮膚炎

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dermal melanocytoses可分成
1. classic Nevus of Ota

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看來似乎是有道理的, 請看下面這篇報導
文章標題

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富含維他命A的食物包括:
蛋黃、動物肝臟、深綠色蔬菜、深橙黃色蔬果、深橙黃色根莖類,例如胡蘿蔔、芒果、木瓜、南瓜、地瓜、玉米。

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ASST方法
Historically, in 1986, Grattan et al. [6] were the first to use ASST to differentiate autoimmune urticaria from chronic idiopathic urticaria. They injected intradermally 0.1 ml of autologous serum and normal saline as control in 12 patients of chronic idiopathic urticaria. The positive results were arbitrarily defined as formation of a wheal by serum within 2 h of injection that is at least 5 mm larger than that resulting from saline control and had a difference of 10 mm in the diameter of surrounding erythema. They observed positive responses in 7 patients within 30 min which attained their zenith in 90-120 min and remained positive for an average of 8 h. Subsequently, Sabroe et al. [7] standardized its methodology and defined the parameters which provide optimum sensitivity and specificity for detecting patients of chronic urticaria with autoantibodies [Table 1]. [4] There have been numerous modifications in the methodology and interpretation of ASST since then in various studies. O'Donnell et al. [8],[9] from their two separate studies interpreted positive ASST as the mean diameter of serum-induced wheal being at least 2 mm larger than that of saline-induced wheal at 30 min. Bakos and Hillander [10] used 0.1 ml instead of 0.05 ml each of serum, histamine and saline. Toubi et al. [11] also used 0.1 ml of sterile autologous serum and determined the wheal/flare size at 30 min and followed up for 60 min and graded the responsed from 0 to +3 of ASST by measuring wheal/flare diameter as 0 = negative control; +1 = wheal 1.5 mm > negative control, flare 15 mm; +2 = wheal 3-5 mm > negative control, flare > 15 mm; +3 = wheal 6-10 mm > negative control.

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Hopkins and colleagues[1] examined response to syphilis therapy among 256 patients in Ireland; they reported 15.5% loss to follow-up and 22% "treatment failure."

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同樣的, 雖然大部分都說女性避孕就好, 但是
Ultrastructural study on cytotoxic effects of cyclosporine A in spermiogenesis in rats

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雖然以前都說女生避孕就好,但是
A small study of acitretin's effect in eight men showed no changes in sperm concentrations {65}. However, for male patients taking acitretin, it is not known whether residual acitretin in seminal fluid during treatment or after treatment has been discontinued poses a risk to a fetus. The maximum acitretin concentration observed in human seminal fluid from systemic use of acitretin or etretinate was 12.5 nanograms per mL, which would transfer approximately 125 nanograms of acitretin per 10 mL of ejaculate. Of the four reported cases with known fetal outcomes in pregnant women whose male partner took acitretin, one infant was normal, two spontaneous abortions occurred, and one fetus had bilateral cystic hygromas and multiple cardiopulmonary malformations. {72}

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C.B ointment亦新增警語

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Int J Dermatol. 2008 Jan;47(1):61-3.

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Dietary amino acid-induced systemic lupus erythematosus.
The effects of dietary manipulations on autoimmune disease are understood poorly. In this article, we detail our experience with a human subject who developed autoimmune hemolytic anemia while participating in a research study that required the ingestion of alfalfa seeds. Subsequent experimental studies in primates ingesting alfalfa sprout seeds and L-canavanine (a prominent amino acid constituent of alfalfa) is presented. The results of these studies indicate a potential toxic and immunoregulatory role of L-canavanine in the induction of a systemic lupus-like disease in primates

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A major cause of neonatal morbidity and mortality in Lagos, Nigeria, is severe neonatal jaundice seen in G-6-PD deficient babies. The observation that the jaundice is more severe in outpatient than in inpatient babies suggests that its cause is exogenous. "Mentholated" powder which is commonly used in many clinics and at home to dress umbilical cords was suspected to be the offending agent. A controlled study of the effects of one of these powders was carried out on 60 consecutive G-6-PD deficient babies. In 30 of them the umbilical cords were dressed daily with the powder while the remaining half who were untreated served as controls. The treated babies developed statistically more significant jaundice than the controls. Inability of neonates to conjugate menthol in this power is probably responsible for the jaundice developed by these G-6-PD deficient babies. It is concluded that the use of menthol and/or camphor-containing commerical products on neonates be discontinued, especially in communities where the incidence of G-6-PD deficiency is high as the use of such products may be contributiing to the severity of neonatal jaundice.

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皮膚也需要鈣?
相信大家都被『天天吃阿鈣,我有健康的膝蓋』的廣告疲勞轟炸過,

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Daily supplementation with 1 to 5 mg of folate has reduced nausea, vomiting, stomatitis and oral ulceration, elevated transaminases, and mild myelosuppression without compromising the efficacy of methotrexate.8-11 Liver fibrosis, pneumonitis, and moderate to severe myelosuppression are not mitigated by folate supplementation. Elevated homocysteine levels, common with methotrexate use and an independent risk factor for coronary artery disease, are decreased with folate supplementation.32
Folinic acid should not be given on the same days as methotrexate dosing. Unlike folinic acid, folate does not compete with methotrexate for cellular uptake. Folate is also considerably cheaper than folinic acid. For these reasons, folate supplementation is preferred by many authorities. One drawback to folate supplementation is the potential masking of vitamin B12 deficiency. Use of folate supplementation with methotrexate therapy is increasing rapidly. Methotrexate overdose is more likely in patients with declining renal function, in those who misunderstand dosing directions, or in those concomitantly exposed to a second folate antagonist, such as trimethoprim-sulfamethoxazole. Overdose should be treated promptly with folinic acid (leucovorin). Folinic acid is metabolized in vivo to tetrahydrofolate in the absence of dihydrofolate reductase, providing an alternative supply of DNA and RNA precursors. Folinic acid should be given early, preferably within the first 24 to 36 hours after overdose. Folinic acid itself has very little toxicity. Therefore, an oral dose of 10 mg/m2 should be given on first suspicion of methotrexate overdose without delay for a serum assay. Peroral or parenteral doses may be continued every 6 hours until the serum concentration of methotrexate falls to less than 10-8 M.7 Practically speaking, or when a serum assay is unavailable, this recommendation is often equivalent to 15 to 25 mg of folinic acid by mouth every 6 hours for 6 to 10 doses.

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懷疑femal hirsutism時可抽free testosterone, DHEAS, TSH
Diagnostic procedures in women affected by hirsutism are performed to determine the cause in order to plan the treatment.

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Scoring systems can assess the severity of hirsutism.

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no arrector pili m.
no graying change

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tx of Botox related ptosis: α2-agonist
1. aprachlonidine 1gtt q6h x2-3wk

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