皮膚科 劉權毅醫師

何時要order SEP


正常的 SEP


不同的peak個代表什麼


In the interpretation of serum protein electrophoresis, most attention focuses on the gamma region, which is composed predominantly of antibodies of the IgG type. The gamma-globulin zone is decreased in hypogammaglobulinemia and agammaglobulinemia. Diseases that produce an increase in the gamma-globulin level include Hodgkin’s disease, malignant lymphoma, chronic lymphocytic leukemia, granulomatous diseases, connective tissue diseases, liver diseases, multiple myeloma, Waldenström’s macroglobulinemia, and amyloidosis

monocalonal vs. polycloncal gammopathy
It is extremely important to differentiate monoclonal from polyclonal gammopathies. Monoclonal gammopathies are associated with a clonal process that is malignant or potentially malignant. In contrast, polyclonal gammopathies may be caused by any reactive or inflammatory process, and they usually are associated with nonmalignant conditions.

An M protein is characterized by the presence of a sharp, well-defined band with a single heavy chain and a similar band with a kappa or lambda light chain. A polyclonal gammopathy is characterized by a broad diffuse band with one or more heavy chains and kappa and lambda light chains

polycloncal gammopathy 有哪些


monocloncal gammopathy 的鑑別診斷疾病


參考網站
http://www.aafp.org/afp/2005/0101/p105.html

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