Monocytosis is the state of excess monocytes in the peripheral blood. It may be indicative of various disease states. Examples of processes that can increase a monocyte count include:

1. chronic inflammation: ulcerative colitis, reginal enteritis, SLE, sarcoidosis
2. stress response
3. hyperadrenocorticism
4. immune-mediated disease
5. pyogranulomatous disease
6. necrosis
7. red cell regeneration
8. Viral Fever: infectious mononucleosis, mupms, measles
9. sarcoidosis
10.congenital Gaucher dz, neoplastic monocytic leukemia, myeloid metaplasia, recovery from agnulocytosis
11.bacterial infection: subacute bacterial endocarditis, TB, brucellosis, syphilis
12.Protozoal infection: malaria, kala-aczar, trypanosomiasis
A high count of CD14+CD16++ monocytes is found in severe infection (sepsis)[5] and a very low count of these cells is found after therapy with immuno-suppressive glucocorticoid







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