皮膚科 劉權毅醫師

Heavy chain disease is characterized by increased amounts of a specific heavy chain -with no light chains.
1. Gamma HCD is associated with autoimmune diseases including AIHA, Sjogrens syndrome, rheumatoid arthritis, SLE, thyroiditis, etc.
2. alpha HCD is characterized by a GI lymphoma known as Mediterranean lymphoma and is associated with an abdominal mass; malabsorption; diarrhea.
Anemia, fever, lymphadenopathy, splenomegaly are common findings with the HCDs.

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